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HCQ/Zinc Quercetin/Zinc Quercetin/vitamin C and how they work in the body.

Hydroxychloroquine

Common brands: Plaquenil

Description

Immunosuppressive drug and Anti-parasite

It can treat and prevent malaria. It can also treat lupus and arthritis.

Brands: Plaquenil

Availability: Prescription needed

Pregnancy: No known risks

Alcohol: Interactions can occur

Drug class: Quinoline

CQ (Chloroquine) and it's metabolite HCQ (Hydroxychloroquine sulfate) combined with Zinc.

CQ and HCQ (CQ/HCQ) inhibit pH-dependent steps of SARS-CoV-2 replication by increasing pH in intracellular vesicles and interfere with virus particle delivery into host cells. Besides direct antiviral effects, CQ/HCQ specifically target extracellular zinc to intracellular lysosomes where it interferes with RNA-dependent RNA polymerase activity and coronavirus replication. {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202847/}.

Drug interactions between HCQ and ascorbic acid Vitamin C

{https://www.drugs.com/drug-interactions/hydroxychloroquine-with-vit...}. None have been observed. However other drugs and HCQ do inter-react. read the article to see which do.

Quercetin;

Quercetin is a plant flavonol from the flavonoid group of polyphenols. It is found in many fruits, vegetables, leaves, seeds, and grains; red onions and kale are common foods containing appreciable amounts of quercetin. Wikipedia

Molar mass: 302.236 g/mol

Formula: C₁₅H₁₀O₇

Solubility in water: Practically insoluble in water; soluble in aqueous alkaline solutions

Melting point: 316 °C (601 °F; 589 K)

Classification: Flavonoid

Pronunciation: /ˈkwɜːrsɪtɪn/

Quercetin with Vitamin C;

Quercetin is a well-known flavonoid whose antiviral properties have been investigated in numerous studies. There is evidence that vitamin C and quercetin co-administration exerts a synergistic antiviral action due to overlapping antiviral and immunomodulatory properties and the capacity of ascorbate to recycle quercetin, increasing its efficacy. Safe, cheap interventions which have a sound biological rationale should be prioritized for experimental use in the current context of a global health pandemic. {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318306/}

Quercetin with Zinc;

Quercetin (a widely used herbal) acts as a zinc ionophore, the same mechanism of action that chloroquine and hydroxychloroquine have via helping zinc pass the cell wall where it can halt viral replication.

Studies have found that Quercetin acts like an ionophore with Zinc. An Ionophore is a lipid-soluble substance capable of transporting specific ions through cellular membranes.

Zinc and SARS-CoV-2;

A Coronavirus is an RNA virus. That means it replicates copies of its own genetic material – RNA, using a replicase enzyme (RNA-dependent replicase / RNA polymerase). The replicase begins to produce multiple copies of the virus. The more viruses will multiply, the more infected host cells will be. Massive immune response and cytokine influx will cause havoc in lung cells, which is associated with worse disease course and may result in the patient’s death. By stopping the virus replication process, it would be possible to alleviate the symptoms of the disease and reduce mortality. It turns out that zinc inhibits replicase’s activity. An obstacle to the action of zinc is the problem with the penetration of this element into the cell. What is needed here is a substance that causes the zinc to transfer from the external environment of the cell to its interior, where the virus potentially replicates. These substances are so-called ionophores, and their function is to transport ions through the cell membrane. {https://swietylukasz.pl/en/2020/03/20/zinc-and-covid-19-infection/}

From there you can make your own decision about what you want your doctor to do.

Remember do not try to Self Medicate!!!

You can overdose, or there can be dangerous interactions with the medicines you are already taking, that may cause permanent damage to your system and even death from overdoses.

You need to do anything like this under a doctors care.